The tendency of actin to polymerize initially thwarted crystal production. Holmes and colleagues overcame this by complexing rabbit skeletal actin with DNase I, thereby preventing polymerization and ...

Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin. The actin filament is a double-stranded helical structure ...

Researchers from Tokyo Medical and Dental University (TMDU), collaborating with scientists from the Marine Biological Laboratory (MBL) and RIKEN, develop a novel technique for live-cell fluorescent ...

This is a preview. Log in through your library . Abstract Arp2/3 complex nucleates branched actin filaments that provide pushing forces to drive cellular processes such as lamellipodial protrusion and ...

Researchers have visualized at the molecular level how formins bind to the ends of actin filaments. This allowed them to uncover how formins mediate the addition of new actin molecules to a growing ...

Cells rely on a network of tiny filaments to give them form and support their structure. One crucial filament is a protein called actin. Researchers have now devised a new way to monitor the movements ...

In previous equilibrium binding studies, Dictyostelium discoideum plasma membranes have been shown to bind actin and to recruit actin into filaments at the membrane surface. However, little is known ...

The dynamic processes that occur during the growth of actin, via polymerization, and the breakdown of actin both play significant roles in cellular mechanisms like migration and adhesion. Due to the ...

Cell migration depends on structures called focal adhesions that connect a cell to the surrounding extracellular matrix. Microtubules—long, thin polymers found in and around cells—help disassemble ...

1 Department of Health Sciences, University of Jaén, Jaén, Spain 2 Basic Cardiovascular Research Section, Department of Morphological Sciences, School of Medicine, University of Granada, Granada, ...