A high-yield, one-pot, scalable reaction facilitates the production of biologically relevant amide compounds using less reactive nitrogen-containing heterocyclic compounds and carboxylic acid without ...

A compound which features multiple bonds between lead and carbon has been isolated and characterised. This heteronuclear ...

New practical approaches to the synthesis of complex heterocycles are reviewed. Medicinal chemistry generally involves the preparation of a lead drug candidate on a milligram scale and uses ...

Organocatalysts consisting of organic compounds without metal elements are receiving much attention as next generation catalysts in the hope of reducing environmental burden and coping with exhaustion ...

Chemists have increased their power to make a variety of compounds by figuring out how to add a single carbon to simple amides, creating four new C bonds in a single step. Mamoru Tobisu and coworkers ...