Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

Delivering a connection-building protein to star-shaped cells in the brain could reverse changes to neural circuits seen in ...

Researchers from Wuhan Institute of Biomedical Sciences, Jianghan University and collaborators recently showed that activating the endogenous transcription factors Ngn2 and Isl1 via CRISPRa can ...

Astrocytes in the adult brain show cellular plasticity; however, whether they have the potential to generate multiple lineages remains unclear. Here, we perform in vivo screens and identify DLX2 as a ...

The human brain contains about 86 billion neurons. These cells fire electrical signals that help the brain store memories and send information and commands throughout the brain and the nervous system.