A preclinical model developed at UT Southwestern Medical Center that recapitulates a rare infant-onset form of diabetes ...

In type 1 diabetes, the immune system attacks the beta cells that produce insulin in your pancreas. The attack causes permanent damage and leaves your pancreas unable to produce insulin.

In type I diabetes, the body’s immune system attacks insulin-producing pancreatic beta cells—a subtype of islet cells. To restore insulin production and simultaneously curtail an immune response, ...

In this type of diabetes, the immune system specifically destroys insulin-secreting beta cells in the pancreatic islets — the body's own immune system attacks its own cells (a form of autoimmune ...

Increased levels of glucose in the circulation lead to increased glucose uptake into pancreatic beta cells through GLUT2, a glucose transporter. Increased intracellular glucose then leads to ...

as are pancreas-after-kidney transplants. Islet or beta cell transplantation, an experimental treatment for Type 1 diabetes, transfers pancreas cells from one person to another, with the new cells ...

Function Features of cell that allow it to perform its function Beta cell (in pancreas) Animal Releases hormone insulin Uses its genetic instructions to assemble insulin Skeletal muscle cell ...