Bile acids are amphipathic steroid molecules synthesised from cholesterol in the liver and secreted into the intestine where they facilitate lipid digestion and absorption. Primary bile acids are ...

Bile acids are essential molecules the liver produces that play a critical role in digestion. They help us absorb fat-soluble vitamins and cholesterol from our food. However, bile acids can become a ...

Bacteria naturally present in the human intestine (known as the gut microbiota) can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking ...

Cholestatic liver diseases, including primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), are ...

Cholic acid (3α,7α,12α-trihydroxy-5β-cholan-24-oic acid) is a bile acid produced in the liver from cholesterol 1. Reports of the identification of cholic acid began to appear in the late 1800s; in ...

Immunotherapy is a modern approach to cancer treatment that uses a patient's own immune system to help fight tumors. It has made an incredible impact on treating cancers in many different organ ...

This article highlights the ZenoTOF 8600 system's ability to detect, measure, and structurally describe bile acid levels in human plasma. Bile acid analysis in human samples has grown increasingly ...