Researchers have developed a quick and simple method for measuring bile acids in biological fluids that can be used to rapidly diagnosis a severe fat storage disorder that can lead to liver disease in ...

Bile acid diarrhoea (BAD) is a prevalent but poorly understood cause of chronic diarrhoea; bile acid malabsorption occurs in ileal disease, but the primary disorder without malabsorption is more ...

Clinical researchers at King's College London and Guy’s and St Thomas’ have found a better way to measure the risk of stillbirth for women with a common liver disorder through a simple blood test. The ...

Bile acids are essential to digestion, by acting like a kind of detergent that breaks up fat molecules. Fat doesn't dissolve in water, but our digestive system is full of water, so the fat we consume ...

Researchers from Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California San Diego have uncovered thousands of previously unknown bile acids, a type of molecule used by ...

There are trillions of microbes in the gastrointestinal tract, and we are starting to learn more about the exact mechanisms that link those microbes and the substances they generate to changes in ...

The intestine-selective FXR knockout mice were generated by cross-breeding of mice with loxP sites flanking the last FXR exon, containing the ligand-binding domain (described by Sinal et al 4), with ...

Scientists have discovered a new role for bile acids: they curb appetite by entering the brain. Their findings provide new insights into the signals and mechanisms by which satiety is controlled and ...

A receptor activated by bile acids can reduce fat-tissue inflammation and insulin resistance in obesity-linked diabetes, research has shown. Diabetes develops when the body has problems with insulin, ...