Bacteria control the homeostasis of membrane lipid biophysical properties by altering the chain length of fatty acids, as well as the ratio of saturated:unsaturated fatty acids. The de novo ...
One significant obstacle in creating these improved lipids was synthesizing branched ionizable lipids, essential components of LNPs that alter their charge to facilitate endosomal escape.
Glycans are sugar chains that bind to cells through proteins or lipids, influencing their chemical properties. These complex, ...