a preferential COX-2 inhibitor, in the treatment of musculoskeletal disorders or postoperative pain. Preliminary data on the use of meloxicam in patients at risk of cardiovascular thrombotic ...

COX-2 is involved in prostaglandin synthesis and expressed throughout the nervous system, where it participates in pain sensitivity and in synaptic plasticity. Microsomal prostaglandin E synthase ...

Basically, they increase the pain you feel. NSAIDs work on a chemical level. They block the effects of special enzymes -- specifically Cox-1 and Cox-2 enzymes. These enzymes play a key role in ...

a type of nonsteroidal anti-inflammatory drug called a Cox-2 inhibitor, which was approved in 1998. Multiple parts of the ...

Purpose: A summary of the basic science underlying the current controversies regarding cyclooxygenase-2 (COX-2)-selective nonsteroidal antiinflammatory drugs (NSAIDs), including data on their ...