Reviews of Infectious Diseases, Vol. 5, Supplement 4. Bacterial Virulence and Pathogenicity (Sep. - Oct., 1983), pp. S797-S805 (9 pages) An experimental model of pneumococcal bacteremia in guinea pigs ...
As one of the most potent mediators of inflammation, the complement component C5a is a promising target for anti-inflammatory drugs. However, a drawback of using animal models to develop antagonists ...
The complement system constitutes an effective first line of defense against invading pathogens. Its components recognize pathogenic cell surfaces and trigger cell lysis and inflammatory responses 1,2 ...
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