Conan O'Brien was roasted by leading American comics ... as well as wife Liza Powel O'Brien, 54, and son Beckett, 19, as he was honored with the Mark Twain Prize for American Humor on Sunday ...

O'Brien was surprised how much free time Javier Bardem had in Madrid for his "Conan O'Brien Must Go" travel series. “He doesn't have enough work.” ...