Non-steroidal anti-inflammatory drugs, or NSAIDs, are a class of drug that is commonly used (worldwide) to reduce ...

COX-1 and COX-2 enzymes may be blocked by pain medications such as Advil and Vioxx in a more complex manner than was previously understood, a Queen's University study has found.

COX-2 enzymes are more familiar in arthritis, but the enzymes produce inflammation in all damaged tissues, including the brain. Many researchers now see the inflammation as a critical process in ...

The cyclooxygenase enzymes (COX-1 and COX-2) catalyze the committed step in the biosynthesis of prostaglandins. COX-1 and COX-2 are the pharmacological targets of nonsteroidal anti-inflammatory drugs ...

COX-2 enzymes are more familiar in arthritis, but the enzymes produce inflammation in all damaged tissues, including the brain. Many researchers now see the inflammation as a critical process in ...

COX-1, the less celebrated sister, is the target of low-dose aspirin and older drugs, such as Advil and Naprosyn, which inhibit both COX-1 and COX-2 to prevent heart disease.

Although cyclooxygenase-1 has the structural features of a “housekeeping” enzyme, its expression may also be regulated. 11,12 The expression of both cyclooxygenase-1 and cyclooxygenase-2 is ...

The enzyme COX-2 is often present in stressed and atypical cells. It causes pain and inflammation. It suppresses the immune system locally and tells the surrounding tissue to grow more aggressively.

COX-2 is an enzyme in the brain that can be markedly upregulated by inflammatory stimuli and neuroexcitation. Researchers say that the density of COX-2 in the brain may be a biomarker and effect ...

COX-1 and COX-2 enzymes may be blocked by pain medications such as Advil and Vioxx in a more complex manner than was previously understood, a Queen's University study has found.

This project is not being offered for the current term. Please check back next semester for updates. The cyclooxygenase enzymes (COX-1 and COX-2) catalyze the committed step in the biosynthesis of ...