Live-cell labeling sheds light on how our DNA is packed and behaves in cells
A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a ...
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Sweetener saccharin revives old antibiotics by breaking bacterial defences
Saccharin destabilizes bacterial membranes and interferes with DNA replication, causing lysis and impairing virulence traits.
DNA repair protein's unexpected structure may lead to new cancer treatments
A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and ...
Scientists Capture DNA Unwinding for the First Time
Scientists have provided the most detailed account yet of the earliest stages of DNA replication, an essential process for ...
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Saccharin disrupts bacterial cell envelope stability and interferes with DNA replication dynamics
The effect of saccharin on the microbiome has received much attention, but its impact on pathogenic bacterial species is less ...
How the Flowerpot Snake’s Unique DNA Repair Mechanism Works
Researchers at the University of Texas at Arlington discovered how the flowerpot snake, with three sets of chromosomes, can ...
FDA approves first new UTI drug in decades
The Food and Drug Administration (FDA) has approved a new drug for treating urinary tract infections, the first such drug ...
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FDA Approves Blujepa for Uncomplicated UTI in Female Patients
Gepotidacin is an oral, first-in-class triazaacenaphthylene antibiotic that inhibits bacterial DNA replication by blocking 2 different type II topoisomerase enzymes.
Chromatin packing domains in ovarian cancer cells: A new target for therapy
Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, ...