The Packers are likely to rest players too, affecting their defense, since they are locked into the No. 7 seed in the NFC. That’s unfortunate, because this unit would otherwise be a nice streamer against Max Brosmer and the Vikings' lackluster offense this week.

There appears to be increasing sentiment that the Eagles will indeed prioritize rest despite the fact that the Eagles must do their part to win to have a chance at the No. 2 seed in the NFC playoff picture. First, there’s this from NFL insider Mike Garafolo (bold emphasis mine):

The NFL season continues in Week 17 when the Buffalo Bills host the Philadelphia Eagles on Sunday. Start time, how to watch, stream and NFL TV schedule.

The Eagles will likely end the season as the NFC's No. 3 seed, but are still alive in the hunt for the No. 2 seed thanks to their win against the Bills.

The defending Super Bowl champion Philadelphia Eagles clash with the Buffalo Bills today. Find out how to watch for free.

The final week of the 2025 NFL regular season is upon us, and if you’re still alive in a Survivor Pool, the SI Betting team is wishing you the best of luck. Wee

Entering NFL Week 17, the Bills had the best Super Bowl 60 odds of any AFC team at +850 on BetMGM Sportsbook. Philadelphia had the third-best odds at +800. It would not surprise anyone if either team started the playoffs as a top seed in their conference and advanced to the Super Bowl.

The Philadelphia Eagles come in as the NFC East champions, but the Buffalo Bills have work to do to retain their AFC East title when they host this NFL Week 17 matchup. The Eagles (10-5) hit a rough patch and went on a three-game losing skid because of an inconsistent offense but have bounced back to score 60 points in winning their past two games.

A Rams loss to the Falcons on "Monday Night Football" means the Eagles won't face the Seahawks first in the playoffs.