Infertility is a major healthcare concern. Understanding the molecular regulators governing fertilization, early embryonic ...

Embryonic development is a meticulously orchestrated process in which spatial and temporal cues guide cell fate determination and tissue patterning. Central to this process is morphogen signalling – a ...

Only two weeks after fertilization, the first sign of the formation of the three axes of the human body (head/tail, ventral/dorsal, and right/left) begins to appear. At this stage, known as ...

From the moment an embryo starts to take shape, two-way communication is critical for making sure tissues and organs develop correctly. Two of the first physical structures to form in the embryo are ...

The mystery of early embryonic communication is starting to be unraveled thanks to a new stem cell-based model.

Scientists in the Brivanlou lab used light-inducible gene expression (yellow circle) and embryo models to demonstrate that, at the start of gastrulation, body-axis formation requires an interplay ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

Metabolism does more than fuel embryos—it sets their developmental rhythm. EMBL researchers found that a sugar molecule, FBP, controls the pace of spine formation, suggesting metabolism may act as a ...

When sperm meets egg, the start of life is not quiet. Under a special microscope, researchers have watched a tiny light show at fertilization. They see a microscopic flash at fertilization, a burst of ...

A research team led by Associate Professor Hirofumi Nishizono and graduate student Masaki Kato from the Research Support ...