Scientists have refined and enhanced the classification system for a type of pediatric leukemia using genomic and transcriptomic analysis. Compared to adult cancers, pediatric cancers often have ...
Acute myeloid leukemia (AML) starts in the bone marrow, but often quickly moves into the blood, as well. The main treatment for most types of AML is chemotherapy, sometimes along with a targeted ...
Measurable Residual Disease and Fusion Partner Independently Predict Survival and Relapse Risk in Childhood KMT2A-Rearranged Acute Myeloid Leukemia: A Study by the International ...
Allo-HSCT significantly improved survival in real-world pediatric AML, with CR1 patients showing the best outcomes, achieving OS and DFS rates of 84.2% and 73.4%. Matched sibling and unrelated donors ...
When acute myeloid leukemia (AML) relapses, it is more difficult to treat and outcomes are dismal. Scientists at St. Jude Children's Research Hospital have discovered a mutation in pediatric AML that ...
Marius Bill, Krzysztof Mrózek, Jessica Kohlschmidt, Ann-Kathrin Eisfeld, Christopher J. Walker, Deedra Nicolet, Dimitrios Papaioannou, James S. Blachly, Shelley ...
Scientists have found a previously overlooked mutation in a subtype of pediatric leukemia that has implications for identifying high-risk patients. When acute myeloid leukemia (AML) relapses, it is ...
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