Researchers from the University College London have brought us one step closer to understanding how we feel pain. Their study, published in Brain, describes a rare genetic mutation found in a patient ...

Fatty acid amide hydrolase (FAAH) is the main degrading enzyme of the fatty acid ethanolamides anandamide (AEA) and oleoylethanolamide (OEA), which have opposite effects on food intake and energy ...

Chronic cannabis users have reduced levels of an enzyme called fatty acid amide hydrolase (FAAH). The enzyme has been considered for treatment for cannabis dependence because it breaks down substances ...

The research and development arm of Janssen Pharmaceuticals, a Johnson & Johnson company, announced on Sunday (January 17) their voluntary suspension of dosing in two Phase 2 clinical trials of their ...

A new research paper titled "FAAH inhibition ameliorates breast cancer in a murine model" has been published in Oncotarget. Breast cancer is the leading cancer among females worldwide. Disease outcome ...

A woman in Scotland can feel virtually no pain due to a mutation in a previously-unidentified gene, according to a research article. She also experiences very little anxiety and fear, and may have ...

Scientists have learned more about a genetic disorder caused by a mutation in a gene called FAAH-OUT, in which carriers feel minimal or no pain, anxiety, or fear. The mutation reduces the expression ...

Figure 1: An overview of the endocannabinoid pathway and molecules tested in this study. “This study explores the functional relevance and therapeutic potential of FAAH inhibition combined with the ...