In type 1 diabetes, the immune system attacks the beta cells that produce insulin in your pancreas. The attack causes permanent damage and leaves your pancreas unable to produce insulin.

For T1D patients, the trouble begins with an immune system self-attack on pancreatic beta cells, the cells that produce the hormone insulin to regulate blood sugar levels. Without a reliable way ...

Researchers have discovered a previously unknown type of connective tissue cells that surround cancer cells in pancreatic tumors. The newly discovered cells counteract tumor development and may ...

Three Johns Hopkins experts discuss the potential of mRNA-powered therapeutics to produce lifesaving treatments and cures for ...

In a major breakthrough for diabetes treatment, scientists have found a new way to regenerate insulin-producing cells. This ...

In a first, scientists have designed immune cells that protect stem cell transplants from being rejected by the body — and they could someday open the door for a cure for diabetes. The new cells, ...

G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from ...

The disease arises because immune cells attack and destroy the insulin-producing beta cells in the pancreas. Studies are exploring how hematopoietic cells might be used to reprogram the immune system ...

Balancing the immune system ... to attack the CD19- tumors. The team also tested whether their engineered suppressor T cells could prevent immune rejection in transplantation. Using a pancreatic islet ...

For example, type 1 diabetes. This is caused by the body's immune system attacking its own insulin-producing beta cells in the pancreas. To treat the disease symptoms, a patient has to frequently ...