The regulation of PGH secretion is very different ... IL). Human insulin, cortisol, human recombinant leptin, and cyclic adenosinmonophosphate (cAMP) were purchased from Sigma Chemical Co. Aldrich ...

However, whether and how apoA-IV enhances insulin secretion in humans is still unknown ... β-cells partly through the Gαs-coupled GPCR/cAMP (G protein-coupled receptor-cyclic adenosine ...

thereby increasing intracellular cyclic AMP (cAMP) in beta cells leading to glucose-dependent insulin synthesis and release. Additionally, it also decreases glucagon secretion and slows gastric ...

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The chronic hyperglycemia of diabetes is ...