Type 2 diabetes is often associated with obesity and occurs as a consequence of a combined impairment in insulin secretion and insulin action. This results in loss of metabolic control ...

The regulation of PGH secretion is very different ... IL). Human insulin, cortisol, human recombinant leptin, and cyclic adenosinmonophosphate (cAMP) were purchased from Sigma Chemical Co. Aldrich ...

thereby increasing intracellular cyclic AMP (cAMP) in beta cells leading to glucose-dependent insulin synthesis and release. Additionally, it also decreases glucagon secretion and slows gastric ...

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The chronic hyperglycemia of diabetes is ...