A number of experimental techniques that involve measurements in engineered CF cell lines (available through the Center’s Gene Expression Core) and tissues of CF animal models (available through the ...

Mucus is key to keeping our lungs clean and clear of bacteria, viruses, and other foreign particles that can cause infection and inflammation. When we inhale microbes and dust, they are trapped in the ...

This is a preview. Log in through your library . Abstract Defective mucociliary transport contributes to infections and inflammation that destroy cystic fibrosis (CF) lungs. To better understand ...

Lung disease in people with cystic fibrosis (CF) is initiated by defective host defense that predisposes airways to bacterial infection. Advanced CF is characterized by a deficit in mucociliary ...

A number of experimental techniques that involve measurements in CF patients are crucial to advancing CF science – including our understanding of basic aspects of disease pathogenesis, ...

Middle-ear infections caused by Gram-negative bacteria remain among the most common pediatric illnesses worldwide.