SportsLine's model simulates every game 10,000 times and reveals its NFL picks today for spread, over/under and money line

After a long season, we've finally reached the end of the 2025 NFL campaign. After today's action, we'll have the complete playoff picture officially set. That

Seattle Seahawks vs. San Francisco 49ers picks, predictions, odds, win probabilities for NFL Week 18 Saturday game on Jan. 3. Who will win today?

Sam Farmer makes his picks and predictions for the final week of the NFL regular season, with the 49ers beat the Seahawks and the Steelers prevailing.

Overall picks to win: 8-8 in Week 17 (173-82-1 for the season) Picks to win with 1-5 confidence: 4-7 (103-64-1) Picks to win with 6-10 confidence: 4-1 (70-18) Overall to cover the spread: 9-6-1 (130-117-9) Cover-the-spread picks with 1-5 confidence: 8-4-1 (107-93-8) Cover-the-spread picks with 6-10 confidence: 1-2 (23-23-1)

Carolina Panthers vs Tampa Bay Buccaneers picks, predictions, odds, win probabilities for NFL Week 18 Saturday game on Jan. 3. Who will win today?

The Bears are 4.5-point favorites in the latest Lions vs. Bears odds at DraftKings, and the total is 51.5. Before making any Bears vs. Lions picks of your own, make sure to look at the top NFL picks from the SportsLine Projection Model,