The penultimate week of the 2025 NFL regular season is here. USA TODAY Sports provides the early predictions for Week 17.

Full NFL picks for Week 17 with the Christmas Day slate and predictions straight-up and against the spread with playoff pushes coming to a head.

The NFL Week 17 schedule features 10 games on Sunday and one more on Monday night, several of which have a direct bearing on the NFL playoffs

Los Angeles’s path to the AFC West crown runs through Houston. Plus, the Packers can clinch a postseason berth against the Ravens.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 17 on a 53-37 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Seahawks vs. Panthers? Hurts vs. Allen? Picks, predictions, stats and what's at stake for every remaining Week 17 game.

There are numerous games on the Week 17 NFL schedule that carry no postseason ramifications, but that doesn't mean these matchups carry no

For Week 17 NFL betting, SportsLine AI has evaluated the NFL odds and provided NFL betting picks for all 16 games. You can only see the AI predictions for the Week 17 NFL schedule here. After analyzing every game in Week 17, the AI says the Steelers (-3, 34), who have won three in a row, cover comfortably against the Browns.

The first of several major matchups in the NFL in Week 18 takes place on Saturday afternoon, as the Carolina Panthers face the Tampa Bay Buccaneers in a huge NF