Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is a well-established risk factor for atherosclerotic cardiovascular disease. The ...
Figure 1: Requirement of the YVNXXF motif for NPC1L1 endocytosis and cholesterol uptake. The degree of surface localization of NPC1L1 is a snapshot reflecting the balance between its endocytosis and ...
Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is a well-established risk factor for atherosclerotic cardiovascular disease. The ...