Researchers at the University of Oklahoma have developed a breakthrough method of adding a single nitrogen atom to molecules, unlocking new possibilities in drug research and development. Now ...

Heterocycles, molecular rings found in many pharmaceuticals, have a reputation for stubbornly resisting modification. That is, in a heterocycle, heteroatoms of one type aren’t easily swapped for ...

From left: UChicago chemists Mark Levin, Jisoo Woo, and Tyler Pearson discuss techniques to swap nitrogen atoms in molecules—a change often made by drug discovery chemists. Credit: Julia Driscoll For ...

For years, if you asked the people working to create new pharmaceutical drugs what they wished for, at the top of their lists would be a way to easily replace a carbon atom with a nitrogen atom in a ...

As a graduate student at the University of California, Berkeley, Mark Levin started sketching out ideas for how to do something no chemist had ever managed before: swapping one of the carbon atoms in ...

Researchers from the National University of Singapore (NUS) have developed an electrochemical reaction manifold that promotes efficient nitrogen atom insertion into saturated carbocycles to access ...

An unconventional route for modifying pharmaceutically relevant molecules swaps an atom of carbon for one of nitrogen. The resulting derivatives might open up avenues of research in ...

Ming Joo Koh and his team at the National University of Singapore have expanded their skeletal editing efforts to include ...

What are Nitrogen-Vacancy (NV) Centers? Nitrogen-vacancy (NV) centers are atomic-scale defects in the lattice structure of diamond. They consist of a substitutional nitrogen atom adjacent to a vacant ...

Chemists offer two new methods to develop a way to easily replace a carbon atom with a nitrogen atom in a molecule. The findings could make it easier to develop new drugs. For years, if you asked the ...