In their recent article in Journal of Clinical Oncology, Soni et al 1 compared findings from randomized controlled trials (RCTs) in oncology with analogous observational comparative effectiveness ...

However, sometimes data obtained from RCTs are incomplete, contradictory, or absent. Furthermore, the likelihood of the success or failure of the intervention is not identical in all individuals in ...

The pharmaceutical industry is facing growing pressure to make drug development more patient-focused. Traditionally, most observational research has been derived from clinical and payer data, but has ...

Chemoprevention is defined as the use of pharmacological agents (including nutrients) to impede, arrest or reverse carcinogenesis and has been used to test the efficacy of numerous nutrients and other ...

Medical research shapes healthcare every day, but not all studies are created equal. Knowing the differences can help you feel more confident reading health information online and understanding what ...

The GRACE principles lay out 3 questions to help healthcare providers, patients, and other decision makers evaluate the quality of noninterventional comparative effectiveness studies. Nonrandomized ...

After showing two groups of schoolteachers a videotape of an eight-year-old boy, psychologists John Santrock and Russel Tracy found that the teachers’ judgment of the child ultimately depended on ...

Statisticians point out that medical and other observational studies often produce results that are later shown to be incorrect. They now suggest ways to fix the system. S. Stanley Young, assistant ...

Medical research is essential for advancing the understanding of health, diseases, and treatments. There are many types of studies that serve different purposes. Medical research, or health research, ...