Americans spent $6 billion on the acid-reflux drug Nexium in 2012, making it the top-selling branded prescription medication ... as esomeprazole (Nexium) and omeprazole (Prilosec and generic ...

And does it matter whether you chew a Tums or pop a Prilosec for heartburn ... To take the guesswork out of shopping for over-the-counter drugs, we asked our experts to choose the best treatments ...