Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

Defects in the genetic code of such regulatory elements can cause developmental defects and disease. But compared to protein-coding regions, they are difficult to identify because they are often ...

Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. Researchers, using an experiment that elucidated the function of tens of thousands of noncoding ...