Structure-based approaches for drug design and virtual screening give new meaning to Louis Pasteur’s saying “Chance favors the prepared mind.” In silico methods are becoming more efficient in allowing ...

In a major advance for rational drug design, chemists have described several protein structures of a crucial player in cellular processes. The advance could bring new ideas for treatments of diseases ...

Overview of protein engineering strategies. Directed evolution mimics natural selection in the laboratory through iterative rounds of mutagenesis and screening. Rational design uses structural and ...

At the heart of every biological process, from the replication of cells to the functioning of the human brain, lies the intricate world of proteins. Understanding the structure of these molecules, ...