It turned out Notch signaling is essential for glia regeneration and maintenance in planarians—no glial cells were found in the animal following RNAi, while the differentiation of other types of ...

Scientists reveal how flatworms regenerate lost tissue using stem cells and positional signals, offering insights into whole-body regeneration during early life stages.

Forsyth Institute research with the flatworm, planaria, offers new clues for understanding restoration of body structures. Researchers at The Forsyth Institute have discovered how the worm's cells ...

Regeneration of tissues and organs is one of the great unsolved mysteries of biology. Whitehead Member Peter W. Reddien works to shed light on that mystery through research on the planarian Schmidtea ...

We show that self-organization, along with patterning cues, govern progenitor behavior in planarian regeneration. Surgical paradigms allowed the manipulation of planarian eye regeneration in ...