Sickle cell anemia is a genetic condition much more common among Black people in the United States. Although it affects all races the same, Black people may face unique challenges due to disparities ...

Sickle cell pain crises can be extremely severe and painful. Doctors use different treatments, such as pain relievers, and prevention strategies to help people manage these pain crises. A sickle cell ...

Sickle cell anemia, or sickle cell disease (SCD), is a genetic disease of the red blood cells (RBCs). Normally, RBCs are shaped like discs, which gives them the flexibility to travel through even the ...

Data are based on estimates from Piel et al. 1 Alaska is shown separately from the rest of the United States. Summary of Recommended Treatment Approaches for Sickle Cell Disease. Data are from Rees et ...

UCSF Benioff Children’s Hospital Oakland is enrolling patients in an innovative clinical trial that seeks to cure sickle cell disease. The trial is the first in the U.S. to apply non-viral CRISPR-Cas9 ...

The Trump administration has a plan to provide access to new treatments for sickle cell disease, the hereditary condition that has meant a lifetime of excruciating pain and debilitating health issues ...

Makenzie’s first sickle cell pain crisis came without warning. She was scared and felt alone. Not only was the pain excruciating, but her parents weren’t there—her two worst fears at once. She spent ...

Here, we describe the first two patients, one with TDT and the other with SCD, who were infused with CTX001 (autologous CRISPR-Cas9–edited CD34+ HSPCs that were genetically edited to reactivate the ...

June 19 is marked as World Sickle Cell Awareness Day, granting the opportunity to reflect on the current state of treatment, access, equity, and more that impacts patients living with sickle cell ...

Sickle cell disease refers to a group of genetic disorders that affect hemoglobin production and the amount of oxygen red blood cells can carry. Sickle cell disease can cause pain, anemia, and reduced ...

The disease gets its name because when you have SCD, your red blood cells look like a sickle, which is a C-shaped farm tool. Normal red blood cells are round and pliable. With sickle cell disease, ...