The Sleeping Beauty transposon system comprises a Sleeping Beauty transposase that was "resurrected" from inactive copies in fish genomes in 1997. It was designed to insert specific sequences of DNA ...

Researchers at the University of Minnesota Cancer Center and the National Cancer Institute (NCI), part of the National Institutes of Health, have discovered a new method that could accelerate the way ...

Gene therapy of haematopoietic stem cells aims at a life-long therapeutically effective correction of these cells in humans with particular genetic disorders. This therapeutic approach has proved to ...

These papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com. A.J. Dupuy et al ...