The kinetochore is a complex molecular machine that directs chromosome segregation during mitosis. It is one of the most elaborate subcellular protein structures in eukaryotes, comprising more than ...

A research team has clarified a mechanism of how retrotransposons, genetic elements that can 'jump around' chromosomes and are known drivers of evolution, preferentially insert in the centromere. A ...

Probing the last genomic frontier of higher organisms, an international team of scientists has succeeded in sequencing a little understood - but critical - genetic domain in rice. MADISON - Probing ...

A genomic study of human and selected nonhuman primate centromeres has revealed their unimaginable diversity and speed of evolutionary change. In cell genetics, a centromere is the spot where two ...

Centromeres are curious structures. These specially organized chromosomal regions are best known for their unique and critical role in cell division, in which they are well understood to serve as the ...

Super-resolution microscopy image of a mitotic chromosome (white) with the centromeres of each sister chromatid depicted in orange. Each centromere consists of two distinct chromatin subdomains ...

Just like you might use a belt to keep your clothes in place, the centromere holds a pair of chromatids together and attaches it to the mitotic spindle during cell division to ensure that each ...

Cell division produces new cells, which underpin life proliferation and development. Mitosis is the shortest and the most dynamic phase of the cell cycle. During mitosis, chromosomes are evenly ...

The American Biology Teacher, a nationally recognized journal, offers articles on recent advances in biology and life science, instructional activities for the classroom and laboratory, and ...

Researchers propose a two-step regulatory mechanism for non-Rabl configurations of centromeres in the nucleus. Centromeres are chromosomal domains that link pairs of sister chromatids together during ...

Richard Feynman’s dictum, “What I cannot create, I do not understand,” resonates with synthetic biologists, who seek to create artificial versions of natural living systems. One of these systems is ...