Researchers at the Salk Institute and King Abdullah University of Science and Technology (KAUST) in Saudi Arabia have discovered a new underlying cause of Wiskott-Aldrich syndrome, a rare genetic ...

Researchers have discovered a new underlying cause of Wiskott-Aldrich syndrome, a rare genetic disease that leads to bleeding and immune deficiencies in babies. Their findings revolve around how cells ...

(HealthDay News) — Gene therapy may benefit children and teens with Wiskott-Aldrich syndrome, a rare immunodeficiency caused by mutations in the WAS gene, according to a small new study published in ...

Arp2/3 complex nucleates branched actin filaments important for cellular motility and endocytosis. WASP family proteins are Arp2/3 complex activators that play multiple roles in branching nucleation, ...

Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 (WH2) is a small and widespread actin-binding motif. In the WASP family, WH2 plays a role in filament nucleation by Arp2/3 complex. Here we ...

DURING the past decade more than 50 cases of the Wiskott—Aldrich syndrome have been reported in the medical literature. The manifestations of the disease begin in the first week of life. Most commonly ...

SEX-linked, hereditary thrombocytopenia is a rarely reported disorder. Only 3 cases have been described. 1–3 More commonly reported is the Wiskott–Aldrich syndrome, 4,5 in which sex-linked, hereditary ...