An unprecedented molecular view of the critical early events in gene expression, a process essential for all life, has been provided by researchers at Georgia State University, the University of ...

Our Assistant Editor, Aisha Al-Janabi, discusses the recent applications of cryogenic electron microscopy (cryo-EM) and cryogenic electron tomography (cryo-ET) to uncover how cells function, as well ...

Getting a detailed look at human proteins is often key to designing drugs that target them. For decades, drug developers have typically relied on X-ray crystallography for that purpose—a technique ...

Limb-girdle muscular dystrophy type 3 (LGMD D3) is a rare disease causing progressive muscle weakness, caused by point mutations in the hnRNPDL-2 protein. A member of the RNA-associated ...

Life science research relies upon advanced imaging technologies for detailed insights into the structure and function of organs, tissues, cells, and sub-cellular molecules. High-resolution 3D images ...

Structure of the poxviral core protein A10. The three subunits of the trimer (colored differently) are represented as simulated cryo-EM surfaces in front of a raw cryo-EM micrograph. The cryo-EM ...

The University of Cincinnati College of Medicine has established the latest innovation in microscopy as the focal point of the Center for Advanced Structural Biology (CASB). The college has purchased ...

The visualization revealed that virulence activation is achieved through the interaction of ToxR or TcpP with the ...

New research from the University of Minnesota School of Dentistry and Masonic Cancer Center is providing important new insights into the structure of a human virus that causes blood cancer. In their ...