Many drugs work by targeting proteins. Biologic medicines showed that proteins can be made into therapies too—in some cases using proteins from the body. Juvena Therapeutics works with a type of ...

N-glycosylation is one of the most common posttranslational modifications encountered on biopharmaceuticals. While the modification is often critical to achieve efficient folding and secretion of the ...

PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, perspectives, reviews, colloquium papers, and actions of the Academy. In ...

A Sino-U.S. study has shown that the increased expression of the small secreted glycoprotein follistatin-like 1 (FSTL1) is critical in the pathogenesis of multiple fibrotic and systemic autoimmune ...

This is a preview. Log in through your library . Abstract Synthesis of the surface glycoprotein GP of Ebola virus (EBOV) is dependent on transcriptional RNA editing, whereas direct expression of the ...

Here we report that Reelin-Dab1 signaling regulates the proliferation and radial distribution of OPCs in the late embryonic mouse neocortex. OPCs express Reelin signaling molecules and respond to ...

Muna Therapeutics has raised $73 million to develop small-molecule treatments for Alzheimer’s and other neurodegenerative diseases. The series A will bankroll work on drugs to repair neuronal ...