Individual members of the Toll-like receptor (TLR) family have different subcellular locations but most of these receptors activate a common signalling pathway through the adaptor protein myeloid ...
Toll-like receptor 4 (TLR4) signalling involves two branches. The early recruitment of the adaptor proteins TIRAP and MYD88 to plasma membrane-resident TLR4 promotes the expression of pro-inflammatory ...
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