Over 80% of patients with relapsed/refractory multiple myeloma responded to anti-GPRC5D CAR T-cell therapy after failure of anti-BCMA CAR T-cell therapy. The investigational therapy showed superior ...

IGF1R is a transmembrane receptor found on the BBB, a semi-permeable membrane between the blood and the network of fluid-filled spaces and connective tissue that surrounds the brain and is ...

Medulloblastomas are childhood tumours of cerebellar origin that are, in some cases, associated with inappropriate activation of the Hedgehog (Hh) signalling pathway. Philip Beachy and colleagues ...