Based on the above findings, a final diagnosis of ovarian sex-chord tumor (Sertoli-Leydig cell), stage IA with heterologous elements of gastrointestinal type, intermediate grade, was made.

Traditional views hold that in females, FSHR is expressed in granulosa cells and controls the maturation of Graafian follicles, granulosa cell proliferation, and estrogen production (Simoni et al., ...

A research team has successfully induced self-location illusions with multi-sensory virtual reality (VR) in an MRI scanner and observed corresponding changes in the human brain's grid cell activity.

Unless you are an aficionado of the Patriot Act (USA PATRIOT Act of 2001, Pub L 107-56, 115 US Stat 272), or routinely involved in eavesdropping litigation, (18 U.S.C. 2518, et.seq; the Stored ...

Next, living reporter cells were used to screen the effects of over 1,000 small-molecule substances on 61 proteins relevant to cancer cells, aimed to uncover potential therapeutic targets.

G-cells: These sit in the stomach’s pylorus region and produce the hormone gastrin. Gastrin can increase hydrochloric acid production by stimulating ECL-like cells to release histamine.

QuantiGene 2.0 plex assay Expression of Phosphodiesterases on human testis (n=4) or Leydig cells tumours (n=4) was analyzed by a custom QuantiGene Plex Assay (QGPA,Affymetrix, Santa Clara, CA, USA) ...

genes are activated. It was unknown if the cluster alone or the cluster plus other elements was required for the cells to learn and remember where they are. The researchers discovered that these ...

Summary of Results OR-449 exhibits striking anti-proliferative activity in the rat Leydig tumor cell (LCT) line R2C, inhibiting DNA synthesis by >90% at 1 mM with an estimated IC 50 of 68 nM.

SARS-CoV-2 infection in Sertoli, Leydig and peritubular myoid cells. a) Immunofluorescence against S-protein evidencing weak labeling in peritubular myoid (pink arrowhead) and Leydig cells (green ...

To try to generate Leydig cells in vitro, Takaki Ishida, MD, from Kobe University, Japan, and colleagues used a two-step protocol employing clones of human induced pluripotent stem cells (iPSCs).