Discover the latest Detroit Lions Week 1 odds, betting lines and expert picks for the 2025 NFL season opener. Lions vs.

The odds for NFL Week 1 have already been released at various New Jersey sportsbooks. While we still have over a month until ...

It's Browns vs. Bengals in the "Battle of Ohio" right off the bat in 2025. Our expert give his best bets for that game, as ...

We try to get ahead of expected line moves leading into Week 1 by locking in some best bets during the down time of the ...

Sammy P delivers some early best bets for the 2025 NFL season. Find out why he's backing three underdogs to cover in Week 1.

Best NFL Week 1 against the spread bets Kansas City Chiefs (-2.5) vs. Los Angeles Chargers (-110 at Fanatics) San Francisco 49ers (-1.5) vs. Seattle Seahawks (-108 at DraftKings) ...

Also at the BetMGM, in tickets, this matchup is the most-bet game of the entire opening-week slate and the point total is the second-most-bet in Overs. Let's take a closer look at the odds at BetMGM ...

2025 NFL futures: Aggregate point spreads provide another component for analyzing teams, odds SportsLine has crafted a season-long NFL spread formula that can serve as a data point for team rankings.