Osteoarthritis (OA), a common degenerative joint disease that affects millions of people worldwide, particularly targets the ...

1 Department of Orthopedics, The Second Hospital of Jilin University, Changchun, Jilin, China 2 Joint International ... of articular cartilage or primarily facilitates tissue repair. While some ...

it can cause synovial inflammation, osteophyte formation, cartilage degradation, leading to OA. (Created with BioGDP.com). Therefore, inhibition of NLRP3 activity or blockade of its upstream signaling ...