"Alexis was our hero and it's a huge wound, an open gaping wound, in our family," the actress tells PEOPLE. Rosanna Arquette and her family are continuing to mourn the death of their sister ...

The Wedding Singer' Cast: Where Are They Now? David Arquette Says His Late Sister, Trans Activist Alexis, Is an 'Inspiration': 'I Miss Her Every Day' Patricia Arquette Says She's Just Now ...

At the height of her acting success, Arquette suffered several heartbreaking losses, one being her beloved sister, Alexis ...

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