A multi-institutional team developed a chimeric antigen receptor (CAR) T cell-based strategy for specifically targeting AML cells in patients who relapsed following other treatments. The team ...

Array Bridge is testing promising drug candidates that can effectively bind and even degrade target proteins, but not via their active sites.

Discover how an emerging technology called tRNA therapy could become the next big thing in genetic disease treatment.

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, but effective treatments are lacking. Cardiac lymphatics play a crucial role in ...

This important study shows that the Nora virus, a natural Drosophila pathogen that also persistently infects many laboratory fly stocks, infects intestinal stem cells (ISCs), leading to a shorter life ...

When your social media account starts spewing out nonsensical or threatening status updates, it's safe to assume that it has ...

While DNA sequencing is routine, determining protein sequences remains one of biology’s toughest challenges, says corresponding author Timothy Jenkins of the Technical University of Denmark. InstaNovo ...

A new set of artificial intelligence models could make protein sequencing even more powerful for better understanding cell biology and diseases.

Researchers from Prof. Yardena Samuels’s lab manipulated cancer cells into making themselves visible to the immune system, creating a new approach that gives hope to patients with previously untreatab ...

Another use case was conducted on small pieces of protein, called peptides, displayed on the surface of cells. These help the immune system recognize infections and diseases such as cancer ... model ...

We also are exploring therapeutic options to block fatty acid accumulation and immunosuppressive signals between the cancer cells and the neutrophils," said Zhang, William T. Butler, M.D., Endowed ...

Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger RNA—a prerequisite for protein synthesis in the cell. The poorly ...