Overall age-adjusted mortality rates have fallen, but the poorest parts of the world aren’t sharing in the benefits.

A true test of durability will take many more years, but if the valve holds up, it’s “potentially a game changer,” say ...

The prevalence of calcific aortic stenosis and amyloid transthyretin cardiomyopathy (ATTR‐CM) increase with age, and they often coexist. The objective was to determine the prevalence of ATTR‐CM in ...

Objective To assess the safety and tolerability of treadmill exercise testing and the association of revealed symptoms with outcome in apparently asymptomatic patients with moderate to severe aortic ...

There is currently no way to stop calcification of the aortic valve. If all else fails, the valve must be replaced. To better understand the development of this common disease, researchers from Bochum ...

Aortic stenosis is a disease often diagnosed in its asymptomatic phase due to its distinct murmur and the widespread use of noninvasive imaging. The history, however, is still of paramount ...

Transcatheter aortic valve implantation (TAVI) is now an established treatment option for elderly patients with severe ...

Traditional operative risk calculators, such as the European System for Cardiac Operative Risk Evaluation II (EuroSCORE II), ...

Over the past 15 years, the increasing use of echocardiography has dramatically changed our understanding of the prevalence and progression of aortic-valve stenosis. Aortic stenosis may be due to r ...

As the stenosis progresses, a resting gradient develops across the aortic valve. The left ventricle responds by developing hypertrophy to overcome the stenosis.

Evidence-based recommendations on transcatheter aortic valve implantation (TAVI) for native aortic valve regurgitation. This involves implanting a replacement valve inside the faulty native valve.