Intracellular hormone metabolism is another locus of sex differentiation. Many cells contain the aromatase that converts androgen to estrogen.

Men with late-onset hypogonadism could eventually be treated with stem cells programmed to develop into Leydig cells that secrete testosterone, suggests a new Japanese study.

The real issue here isn’t the ovarian cancer, the Merkel call cancer, or the squamous cell cancer. It’s the breast cancer and its treatment -- an aromatase inhibitor (AI).

This study is looking at proteins called oestrogen receptors in breast cancer, in women taking aromatase inhibitors.

The pituitary gland secretes the hormones luteinizing hormone (LH) and follicle stimulating hormone (FSH) which regulate the number of Leydig cells and their secretion of testosterone.

Orphagen Presents Preclinical Efficacy Data at AACR 2022 on OR-449, a First-in-Class SF-1 Inhibitor, for the Treatment of Leydig Cell Tumors ...

Abstract PURPOSE: To elucidate the biologic association between germ cell neoplasia and testicular dysfunction, through investigation of Leydig cell function and semen quality in men with carcinoma-in ...

This study is looking at proteins called oestrogen receptors in breast cancer, in women taking aromatase inhibitors.