Complementary biochemical and structural findings reveal molecular principles underlying substrate selectivity by a model hyaluronan synthase.

NAEs are lipid-based endogenous signaling molecules that are produced by combining long-chain fatty acids with ethanolamine. Collectively, NAEs include both endocannabinoids and structurally related ...

Findings reveal coronaviruses exploit stress-linked tRNA modifications, enhancing translation efficiency and offering insights for antiviral drug development.

Researchers have found evidence of nuclear metabolic enzymes for the first time, contributing to our understanding of cancer ...

Coronaviruses not only use the machinery of the human cells they infect: they modify them to achieve optimal conditions to ...

Innate immune sensors—known as pattern recognition receptors (PRRs)—detect specific molecular components of bacterial or ...

Osteoarthritis in the jaw joint, or TMJ osteoarthritis, affects millions worldwide, yet effective treatments are limited. Researchers from Boston University now report that a naturally occurring ...

A resurrected ancient enzyme is helping scientists test how reliably Earth’s oldest rocks record signs of life.

Distinguished Professor and founding director of the Rutgers Center for Lipid Research (RCLR), George Carman, recently received the American Society for Biochemistry and Molecular Biology's ...

Marine animals, such as the extremely simple flatworm Trichoplax, are ideal model organisms for studying the early evolutionary origins of animal life processes. Despite measuring only a few ...

HOUSTON—A new research analysis of a sample of Mars gathered by NASA’s Curiosity rover and initially studied by onboard instrumentation has determined that non-biological sources once considered ...

Abstract: This paper tackles the challenge of aligning graph representations of small biological molecules, crucial for understanding structure-function relationships in biological research. We focus ...