Enterochromaffin cells (ECs) are the most abundant subtype of intestinal enteroendocrine cells in the colon, which can be directly contacted by gut microbiota on the side of the intestinal lumen and ...

Heart muscle cells do something similar, issuing electrical “heave-ho” signals that make the organ beat. Skin and other epithelial cells, however, were thought to be silent; they form barrier ...

Molecularly defined serotonin (enterochromaffin) cells of the gut lining were distinguished by single-cell expression analysis, in situ hybridization, and immunohistochemistry into 14 topographically ...

This important study presents a transcriptomic analysis of enterochromaffin cells in the intestine. The evidence supporting the authors' claims is solid, although the functional analysis is focused on ...

Serotonergic enterochromaffin (EC) cells are sensory cells within the gut that detect noxious stimuli and transduce this information to sensory nerve fibers to elicit defensive responses such as ...

We read with great interest the recent excellent work by Stevens et al ,1 in which the authors showed that zonulin and fatty acid-binding protein 2 have a relationship with the increase in ...

During in vitro differentiation, a significant number of cells may acquire an unwanted identity, resembling serotonin-producing enterochromaffin cells, which complicates their application in T1DM ...

Conclusions: To the best of our understanding, this is the first NCDB investigation of Enterochromaffin Cell Carcinoid (ECC) and therefore addresses a meaningful educational disparity on the topic.

The gastrointestinal epithelium constitutes a chemosensory system for microbiota-derived metabolites such as short-chain fatty acids (SCFA). Here, we investigate the spatial distribution of Olfr78, ...

A rare cell type in the gut, the enterochromaffin (EC) cell, drove both gut discomfort and anxiety symptoms in animal models of gastrointestinal pain. Furthermore, the cells reacted differently in ...