Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...
At HIC, we believe in the power of Health Data Research to shape positive and meaningful changes in health care outcomes for us all. Established over 15 years ago, we have built up a wealth of ...
This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...
Health Informatics Conversations are inspiring discussions about current topics in health informatics, kicked off by an inspirational speaker who introduces the topic. The Health Informatics ...
2020). The scaffolded genome has a span of 111 Mbp (117 Mbp including small fragments unincorporated into the HiC assembly) and an N50 of 2.7 Mbp (for contigs >500 bp). The assembly contains 18 ...
Following quality control and filtration of hic tags with HiCUP, valid reads for interaction analysis were aligned to the reference genome (Lieberman-Aiden et al., 2009). The number of reads with ...
Anglerfishes are a highly diverse group of species with unique characteristics. Here, we report the first chromosome-level genome of a species in the order Lophiiformes, the yellow goosefish (Lophius ...
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