Patients with FA had lower dentate nucleus and superior cerebellar peduncle volumes compared to healthy volunteers. The development of the spinal cord and superior cerebellar peduncles is impaired ...

The inferior olive provides the climbing fibers to Purkinje cells in the cerebellar cortex, where they elicit all-or-none complex spikes and control major forms of plasticity. Given their important ...

In the normal mature brain, numerous neural circuits, mostly closed loop, connect a spectrum of motor and nonmotor regions of the cerebral cortex with the cerebellum. Development and consolidation ...

The superior cerebellar peduncle (SCP) is the mainly cerebellar efferent pathway that connects the cerebellum to cerebral regions through the thalamus. In addition, the inferior cerebellar peduncles ...

In contrast, the central axis of motor and nonmotor macroscale organization in the cerebellum remains unknown. Here we applied diffusion map embedding to resting-state data from the Human Connectome ...

Results: Decreased fractional anisotropy (FA) and increased mean diffusivity (MD) were found in the left inferior cerebellar peduncle and superior cerebellar peduncle (SCP) in the pre-SCA3 group ...