Drugs that bind to and activate the receptors for the hormones GLP-1 and GIP are effective in the treatment of obesity and ...

Using retroviral transduction ... We identified key pathways that contribute to this resistance, including: Androgen receptor (AR) activation IGF-I/PI3K/Akt/mTOR signaling Rb inactivation LIM domain ...

presumably generated by summed effects of mutations resulting in activation of receptor tyrosine kinases and signal transduction pathways, may be the aetiology for many human GBMs. Combined ...

The insulin receptor substrate-1 (IRS-1) plays a crucial role in the insulin signaling pathway; however, its function in PAH is still not fully understood. The objective of this research was to ...

Thus, neuronal insulin-like signaling appears to be a key regulator of various essential functions in C. elegans, and the metabolic and reproductive defects induced by whole-body deletion of DAF-2 ...

Epoxyeicosatrienoic acids, or EETs, are signaling ... receptor. This receptor is postulated to be responsible for many of the vasorelaxation and anti-inflammatory effects of EETs. Therefore, its ...

Meta analysis coupled with IPA pathway-network ... estrogen receptor, growth hormone, cytochrome C, AP1, and ADCY appeared four times; TGF-β, ERK, Jnk, MAPK, Akt, PI3K complex, NFκB complex, ...