The study involved a comprehensive dataset constructed from 35 carefully selected academic papers, out of an initial 128, focusing on 13 features related to macrophage polarization. After ...

Crown BioScience experts explore how 3D in vitro assays mimic the suppressive tumor microenvironment to improve drug response ...

Schematic representation depicts the mechanism by which the ENO2-derived oncometabolite PEP directly binds to HDAC1 and thereby promotes H3K18la, which promotes macrophage polarization and leads ...

The new material combines the functions of hydrogen's antioxidant and anti-inflammatory properties and magnesium's promotion ...

In tumor microenvironments, substances like 8-OHG drive macrophage polarization towards the immunosuppressive M2 type. M1 macrophages, with higher ferritin expression, are more resistant to ...